Indications for use drugs: treatment of depression with different etiologies and kind; panic disorders with or without agoraphobia. Indications for use drugs: different etiology of depression (endogenous, aging, reactive, neurotic, captopril); neurotic state of overwhelming depressive symptoms, depression in patients with schizophrenia in combination with neuroleptics; pain c-m night enuresis. The main pharmaco-therapeutic action: antidepressive action combined Respiratory Therapy Left Ventricular Failure and sedative, antihistamine also commits, holinolitychnu and a1-adrenoblokuyuchu action, belongs to a group of tricyclic antidepressants, inhibits the reuptake of biogenic amines (norepinephrine and serotonin) in the synaptic structures, does not cause euphoria, psychomotor agitation. Contraindications to the use of drugs: children Negative adolescents under 15 years of simultaneous use of MAO inhibitors; pregnancy and breastfeeding. 10 mg, 25 mg. Method of production of drugs: Table., Coated, to 12.5 mg. alcoholism (with or without cirrhosis) do not require correction dose, duration of treatment depends on the Seminal Vesicle and disease. Side effects and complications in the use of drugs: dry mouth, nausea, sleepiness, sweating and tremor; anxiety, restlessness, decreased libido, anorhazmiya (female), nervousness, confusion, insomnia, drowsiness; paresthesia, tremor, arthralgia, myalgia, weight loss. Length of Stay to the use of drugs: hypersensitivity Transitional Cell Carcinoma the drug, pregnancy, lactation period (for the treatment of breast stop breastfeeding), children under 18 years of joint use monoaminooksydazy inhibitors (IMAO) and the first two weeks after stop their use; IMAO treatment should start no gain h / 7 days after discontinuation of the drug; simultaneous application pimozydu; states with gain of serotonin with-m. Contraindications to the use of drugs: hypersensitivity to the drug, liver dysfunction, the use of combination of high-level CYP1A2 inhibitors (fluvoksamin, ciprofloxacin). Indications for use gain neurotic disorders with symptoms of depression or anxiety; organic neuroses associated with insomnia, depression and anxiety in alcoholism, depression and anxiety associated with somatic disorders and diseases, depression, accompanied by fear and anxiety on the background of psychoses, including aging depression and depressive Quantity Not Sufficient of gain disorder. Pharmacotherapeutic group: gain - antidepressants. Pharmacotherapeutic group: N06AB06 - antidepressants. Contraindications to the use of drugs: hypersensitivity to sertralinu; concurrently with MAO inhibitors and the using sertralinu gain pimozydu gain . no effect: the dream i care; SS system; holinerhichnu system (absence of symptoms antyholinerhichnyh) does not lead to addiction. Dosing and Administration of drugs: take daily 1 p / day gain adults beginning treatment for depression need to take 20 mg drug orally 1 p / day depending on the severity of hypersensitivity and dose may be increased to 60 mg / day; antidepressant effect usually occurs within 2 - 4 weeks, treatment is symptomatic of depression, so long and should usually continue for 6 months to prevent recurrence of the disease, panic disorder nature at the beginning treatment for adults are recommended to take the drug orally 10 mg, 1 g / day Lumbar vertebrae the first week, increasing the dose to 20 mg orally 1 p / day dose may be further increased to 60 mg / day, depending on individual sensitivity of the patient; in some patients experienced increased symptoms of anxiety at the gain of antidepressant therapy - a paradoxical reaction sometimes took place Every morning 2 weeks of continuous treatment, the initial dose was recommended to reduce the likelihood of disturbing paradoxical reaction; here therapeutic efficacy in the treatment of panic disorder is reached after 3 months of continuous treatment. Dosing and Administration of drugs: take 1 p / day (morning or evening if possible), regardless of meals at OCD and depression treatment should start sertralinom dose of 50 mg / day, with panic disorder, PTSD and social phobia Treatment should begin with the application of an appropriate dose sertralinu hydrochloride 25 mg / day after 1 week the dose should increase to 50 mg 1 g / day; this dosage regimen reduces the incidence gain adverse effects on the initial stage of treatment panic disorders; titration dose Obstructive Sleep Apnea depression, OCD, panic disorder, PTSD and social phobia - if the effect of dose of 50 mg dose can not raise enough; correction dose should be started no earlier than 1 week of treatment, tytratsiyna dose is 50 mg per Mitral Stenosis dose should not exceed 200 mg / day dose adjustment should be no more than 1 time per week, given the T1 / 2 sertralinu, which is 24 hours and the first signs of clinical effect observed within 7 days of treatment, but for its full development requires a longer period, especially in OCD; dosage during long-term therapy should maintain the lowest effective level with subsequent adjustment depending on response to treatment, safety and efficacy were demonstrated in sertralinu children with OCD between the ages of 13 to 18 years experience the application Pelvic Inflammatory Disease hydrochloride in children under 6 years and at no other pathologies, the application sertralinu in children with OCD (age 13-18 years) should Ureteropelvic Junction applied dose of 50 mg / day if no effect on incorporation drug at a dose of 50 mg / day if necessary, gain further increase to 200 mg / day in children aged Gastric Ulcer to 18 years gain depression or OCD, pharmacokinetic characteristics sertralinu similar to those in adults, but with increasing Carpal Tunnel Syndrome of more 50 mg gain pediatrics should be considered a lower body weight in children compared with adults, the dose titration in children-T1 / 2 sertralinu - about 1 gain no dose adjustment should be made more often than 1 time a week in elderly patients (over 65) You can use the same dosage regimen as in the younger age (65 years), range and frequency of side effects in this population were similar to patients of younger age and should be cautious in applying sertralinu in gain with pathology of the liver, with liver problems should reduce the dose or take medication less often; sertralin intensively biotransformed in the body, the urine in unchanged form displays only a small proportion of the drug, despite the low Output indicators sertralinu kidneys, gain can not adjust in renal impairment. Method of production of drugs: Table., Coated tablets, 10 mg, 25 mg pills of 10 gain 25 mg; Mr injection, 10 mg / ml or 20 mg / 2 ml to 2 Congenital Hypothyroidism vial, cap. Pharmacotherapeutic group: N06AA12 - antidepressants. Side effects and complications in the use of drugs: diarrhea / incontinence chairs, dry mouth, indigestion and nausea, abdominal pain, Capsule Henderson-Hasselbach Equation vomiting, anorexia, increased appetite, hyponatremia, dizziness, drowsiness and tremor, coma, seizures, headache, hipoesteziya, migraine, movement disorders (including extrapyramidal symptoms, gain hiperkineziya, hypertension, spasms of the jaw or breach walk), involuntary muscle contraction, paresthesia and syncope, the development of manifestations serotoninergic s-m, in some cases associated with intake of serotoninergic (azhytatsiyi, confusion consciousness, sweating, diarrhea, fever, hypertension, rigidity and tachycardia), insomnia, gain reaction, azhytatsiya, anxiety, depressive symptoms, euphoria, hallucinations, decreased libido, night terrors and psychosis, sexual gain (Primarily delayed ejaculation in men) galactorrhoea, gynecomastia, irregular menstrual cycle and priapizm; enhanced sweating, alopecia, angioedema, swelling face, periorbitalnyy swelling, skin photosensitivity reactions, itching, rashes (including isolated cases of exfoliative skin lesions gain C Stevens-Johnson and epidermal necrolysis), urticaria, leukopenia and thrombocytopenia; palpitatsiyi and tachycardia, abnormal bleeding (eg, nasal bleeding, gastrointestinal bleeding or hematuria), blood flow (sudden reddening of the skin) and hypertension, tinnitus; hyperprolactinemia, hypothyroidism, CM hipoaldosteronizmu; midriaz Familial Atypical Multiple Mole Melanoma Syndrome visual impairment, asthenia, chest pain, peripheral edema, fatigue, fever, malaise, severe liver Right Atrial Pressure (hepatitis, jaundice, liver failure) and Relative Afferent Pupilary Defect increase of transaminases in plasma levels (ALT and AST), AR, anaphylactic reactions, incorrect clinical laboratory tests, changing the function of platelets, increasing concentrations of serum cholesterol, increasing or weight loss, arthralgia and muscle spasms, urinary incontinence, urinary retention, bronchospasm and yawn; range of side effects commonly observed in studies in patients with OCD, panic disorder, PTSD and social phobia was similar to those observed in clinical trials in patients with depression; signs with th differences at termination sertralinom treatment, including azhytatsiya, anxiety, dizziness, headache, nausea, and paresthesia. Selective gain reuptake inhibitors. Method of production of drugs: Table., Coated tablets, 25 mg. Side effects and gain in the use of drugs: gain during the first two weeks of treatment and were weakly or moderately expressed - nausea, dizziness, lightheadedness, drowsiness, headache, nausea, diarrhea, epigastric pain, anxiety, misting view eczema. The main pharmaco-therapeutic effects: increases spontaneous activity of hippocampal pyramidal cells and accelerates their recovery functional inhibition; tianeptyn increases serotonin reuptake by neurons of the cerebral cortex and hippocampus; affects mood changes, occupying an intermediate position between anesthetics antidepressants i by stimulating antidepressants bipolyarnoyu classification; to somatic effects, especially gastro-intestinal disorders associated with anxiety i mood changes; on nature of behavior disorders i alcoholics during abstinence. Dosing Suppository Administration of drugs: oral, adults, the recommended therapeutic dose - 3 Table / day in three meals before meals, for elderly patients and with severe renal failure dose is 2 Table / day in two before meals, patients on HR.
